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Preparation of microfluidic chip based on glass substrate

Preparation of microfluidic chip based on glass substrate

  • Categories:News
  • Time of issue:2021-04-30 23:04
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(Summary description)This paper introduces a method for manufacturing microfluidic chips based on glass substrates. Microchannels are etched on the surface of the glass substrate by photolithography. Use oxygen plasma to treat the surface of the substrate where the polydimethylsiloxane (PDMS) and the microchannel are located, so that the surface properties of the PDMS and the substrate are changed from hydrophobic to hydrophilic, and the covalent of PDMS and the glass substrate is completed. Key combination. Experiments show that the PDMS treated with oxygen plasma has a better sealing effect with the glass substrate. Given that PDMS has good thermal stability, non-toxicity, and good optical properties, this microfluidic chip can be used for chemiluminescence and fluorescence detection in the fields of biomedicine and chemistry.

Preparation of microfluidic chip based on glass substrate

(Summary description)This paper introduces a method for manufacturing microfluidic chips based on glass substrates. Microchannels are etched on the surface of the glass substrate by photolithography. Use oxygen plasma to treat the surface of the substrate where the polydimethylsiloxane (PDMS) and the microchannel are located, so that the surface properties of the PDMS and the substrate are changed from hydrophobic to hydrophilic, and the covalent of PDMS and the glass substrate is completed. Key combination. Experiments show that the PDMS treated with oxygen plasma has a better sealing effect with the glass substrate. Given that PDMS has good thermal stability, non-toxicity, and good optical properties, this microfluidic chip can be used for chemiluminescence and fluorescence detection in the fields of biomedicine and chemistry.

  • Categories:News
  • Time of issue:2021-04-30 23:04
  • Views:
Information

This paper introduces a method for manufacturing microfluidic chips based on glass substrates. Microchannels are etched on the surface of the glass substrate by photolithography. Use oxygen plasma to treat the surface of the substrate where the polydimethylsiloxane (PDMS) and the microchannel are located, so that the surface properties of the PDMS and the substrate are changed from hydrophobic to hydrophilic, and the covalent of PDMS and the glass substrate is completed. Key combination. Experiments show that the PDMS treated with oxygen plasma has a better sealing effect with the glass substrate. Given that PDMS has good thermal stability, non-toxicity, and good optical properties, this microfluidic chip can be used for chemiluminescence and fluorescence detection in the fields of biomedicine and chemistry.

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